Alert! 8 Drugs That Cause Serious Dementia

First-generation antihistamines, such as diphenhydramine, are used to treat allergies but can cause cognitive impairment due to their anticholinergic action. A recent study showed that their prolonged use is associated with an increased risk of dementia.

Less harmful alternatives like cetirizine are preferable for long-term allergy treatment. It is important to consult a doctor before taking these medications for an extended period of time.

Tricyclic antidepressants and memory loss
Tricyclic antidepressants, such as amitriptyline, increase the availability of several neurotransmitters but also have anticholinergic effects. This makes them associated with a higher risk of dementia and cognitive impairment, particularly in older adults.

Today, safer alternatives such as selective serotonin reuptake inhibitors (SSRIs) are available and offer a better safety profile.

Statins and cognitive function

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